URSOLYX™ Soft Chews for Cats
This first-in-its-class muscle support features ursolic acid, which targets mRNA expression in skeletal muscle and has shown demonstrated efficacy in multiple species, including cats.1-6 URSOLYX™ Soft Chews leverage this compound to promote muscle function and strength in aging, active or recuperating feline patients.
Virbac created URSOLYX Soft Chews in collaboration with Emmyon, a U.S.-based biotechnology company founded by a physician scientist. Emmyon studies the molecular underpinnings of muscle atrophy. For URSOLYX Soft Chews, we helped translate that research into this feline muscle health supplement.
In a study of Veterinary Healthcare Professional Teams' personal pet felines6:
OVERALL MOBILITY
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82% saw improvement by week 8
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With many seeing improvement in as little as 2 weeks
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And improved ability to run, rise, play and jump
Based on clinical observations, 88% of Veterinarians would
recommend continued use of URSOLYX Soft Chews.
Although joint support is a well-established component of mobility protocols, the complementary necessity of muscle support has been largely unaddressed. Advances in veterinary care are helping patients to live longer,7 heightening the need for comprehensive mobility support. Your Virbac representative will be happy to visit your clinic, answer questions and talk with you about how URSOLYX Soft Chews can complement your existing mobility protocol.
FOR YOUR HEALTH CARE TEAM
FOR YOUR CLIENTS
On-Demand Podcasts:
INSIGHTS FROM A LEADING MOBILITY EXPERT
Learn From the Expert: Why Joints and Muscles Both Matter in Mobility Care
Leilani Alvarez, DVM, DACVSMR
Explore these insightful podcasts highlighting the importance of a multimodal approach;
supporting joints and muscles, while keeping pets moving comfortably through the years.
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REFERENCES:
1. Ebert SM, Nicolas CS, Schreiber P, et al. Ursolic acid induces beneficial changes in skeletal muscle mRNA expression and increases exercise participation and performance in dogs with age-related muscle atrophy. Animals (Basel). 2024;14(2):186. doi:10.3390/ani14020186
2. Yu R, Chen JA, Xu J, et al. Suppression of muscle wasting by the plant-derived compound ursolic acid in a model of chronic kidney disease. J Cachexia Sarcopenia Muscle. 2017;8(2):327-341. doi:10.1002/ jcsm.12162
3. Ebert SM, Dyle MC, Bullard SA, et al. Identification and small molecule inhibition of an activating transcription factor 4 (ATF4)-dependent pathway to age-related skeletal muscle weakness and atrophy. J Biol Chem. 2015;290(42):25497-25511. doi:10.1074/jbc.M115.681445
4. Kunkel SD, Elmore CJ, Bongers KS, et al. Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease. PLoS One. 2012;7(6):e39332. doi:10.1371/ journal.pone.0039332
5. Kunkel SD, Suneja M, Ebert SM, et al. mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass. Cell Metab. 2011;13(6):627-638. doi:10.1016/j.cmet.2011.03.020
6. Data on file. Virbac Corporation.
7. American Veterinary Medical Association. U.S. Pet Ownership & Demographic